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Herpes Zoster Incidence High In Solid Organ Transplant Recipients

2011-02-02T21:03:00.000-08:00

The incidence is highest among African Americans, heart recipients, and older subjects.

The study, led by Steven A. Pergam, MD, MPH, of Fred Hutchinson Cancer Center in Seattle, included a multicenter cohort of 1,077 patients who received an SOT from January 1995 through December 2007 and follow-up care at a Veteran's Affairs hospital. The group included 500 kidney, 461 liver, and 80 heart transplant patients. Thirty-six patients received other organs.

The overall HZ incidence was 22.2 infections per 1,000 patient-years, according to a report in Transplant Infectious Disease (published online ahead of print). The incidence was 37.6 per 1,000 patient-years among African-American subjects. By comparison, the annual incidence in the general population is estimated to be 1.5-3.0 cases per 1,000 person-years.

Compared with white subjects, African Americans had a nearly twofold increased risk, the researchers reported.

Heart transplant recipients had the highest incidence of HZ—40.0 infections per 1,000 patient-years. Compared with kidney transplant recipients, heart transplant recipients had a 70% increased risk of HZ infection after adjusting for multiple potential confounders.

“To the best of our knowledge, this study is one of the largest multicenter cohort of SOT recipients to date to assess the incidence of HZ,” the authors noted. “These data provide important information on long-term risk of HZ following SOT, afford the first assessment of risk in other non-white populations, and present further evidence for an increased risk of HZ in SOT recipients.”

Dr. Pergam and his colleagues also pointed out that their study is the first to reveal a higher incidence of HZ in African-American SOT recipients. This higher incidence could be related to higher rates of organ rejection in this racial group, increased utilization of VA resources, differences in immunosuppressive regimens, or some other undetermined racial variations in viral immune response.

The incidence of HZ declined with time. Subjects who received their organ from 1996-1999, 2000-2004, and 2005-2007 had an incidence of 29.0, 19.1, and 15.2 per 1,000 patient-years, respectively.

The researchers hypothesize that the decreased incidence observed in latter cohorts is likely in part a result of shorter follow-up and increasing use of antiviral cytomegalovirus prophylaxis, which has been shown to further limit HZ risk.

Similar to the general population, the incidence was also highest among patients older than 55 years: 26.3 per 1,000 patient-years. By comparison, the incidence was 20.4 and 19.8 per 1,000 patient-years for patients younger than 45 and those aged 45-55 years.

UAB research: Preventing deaths from Herpes

2010-11-28T18:41:00.000-08:00

"Herpes simplex virus infections that reach the central nervous system are a significant cause of mortality particularly among newborns. While use of acyclovir has improved outcomes, the number of fatalities and cases of permanent neurologic impairment is unacceptably high," said Debra C. Quenelle, PhD, Associate Professor, the University of Alabama at Birmingham School of Medicine. "CMX001 has demonstrated improved efficacy to acyclovir in reducing viral load and reducing viral replication, particularly in the CNS, in studies of Herpes Simplex Virus (HSV) infected mice which have been highly predictive of outcome in humans. Based on these promising results, CMX001 may have potential for use -- either alone or in combination - in the treatment of herpes encephalitis, neonatal herpes, or other severe HSV infections in humans."

California Jury Awards $2.4 Million for Herpes Infection

2010-11-21T16:49:00.001-08:00

A Beverly Hills man has been hit with a $2.4 million judgment in a suit alleging that he negligently infected his soon-to-be-ex wife with genital herpes.

The suit highlights the unsettling prevalence of sexually transmitted diseases (STDs) and the ease with which they can be spread.

Read more: http://www.consumeraffairs.com/news04/2010/11/california-jury-awards-2-4-million-for-herpes-infection.html#ixzz15y4dlPOc

Herpes: Top Natural Supplements for Treatment

2010-11-14T17:49:00.001-08:00

Herpes, one of the most common sexually transmitted diseases, is a virus that affects the mouth and the genital area appearing as sores that ooze and itch. Genital herpes can affect both men and women of any age and spreads through skin-to-skin contact. It does not spread through personal objects such as towels because the virus cannot survive outside the body.

Love, H Style Is the Ultimate Herpes and HPV Social Networking Community

2010-11-03T17:24:00.001-07:00

Love, H Style is helping people worldwide increase awareness about genital herpes, oral herpes, genital warts, and HPV. The free social networking community also gives members a unique opportunity to express their feelings, share stories, date and encourage others in the same situation.

Vical to Update Herpes Simplex Vaccine Program at Keystone Conference

2010-10-27T18:25:00.000-07:00

(GlobeNewswire via COMTEX) -- Vical Incorporated (VICL 2.26, +0.00, +0.01%) today announced that the company's Vice President of Clinical Development, Richard T. Kenney, M.D., is presenting preclinical results from the company's herpes simplex type 2 (HSV-2) vaccine program in a poster session Friday morning at the Keystone Symposium on Immunological Mechanisms of Vaccination (Seattle, October 27 -- November 1).

In Investigational Study, ZOSTAVAX®, Merck's Shingles Vaccine, Reduced Incidence of Shingles in Adults Ages 50 to 59 by Nearly 70

2010-10-21T17:34:00.000-07:00

In a large clinical study of adults ages 50 to 59, ZOSTAVAX® (Zoster Vaccine Live), Merck's vaccine for the prevention of shingles (herpes zoster), reduced the incidence of shingles by nearly 70 percent (69.8) compared to placebo. These new data will be presented on Oct. 23 at the 48th Annual Meeting of the Infectious Diseases Society of America (IDSA) in Vancouver, British Columbia, Canada. Based on these results, earlier this year Merck filed a supplemental Biologics License Application (sBLA) with the U.S. Food and Drug Administration (FDA) for the use of ZOSTAVAX to prevent shingles in people 50 to 59 years of age.

Experimental genital herpes vaccine fails major clinical trial

2010-10-17T18:34:00.000-07:00

An experimental vaccine designed to block genital transmission of herpes viruses from men to women has failed a major clinical trial aimed at obtaining manufacturing approval, researchers said Thursday. Because of the failure, the vaccine's manufacturer, GlaxoSmithKline, said it will abandon any further attempts to develop the vaccine, called Simplirix.

Beech Tree Labs' Oral Herpes Trial Begins

2010-09-22T17:14:00.000-07:00

Beech Tree Labs, Inc. announced today that it has initiated a Phase 1/2a clinical evaluation of its novel therapeutic agent for treating recurrent oral herpes infections. This FDA-approved study is a 210 patient, multi-site, placebo-controlled trial of its agent BTL-TML-HSV.

“While our initial clinical focus in on oral herpes, we have evidence that suggests our patented agent may address a broad range of herpesvirus indications.”
According to WHO and CDC statistics, over 80 percent of the population have oral herpes with about 20 percent of these expressing symptoms. In addition, one of four adults has genital herpes, with the incidence steadily increasing. Treatment options for herpes are limited.

General Infectious Disease

2010-09-15T17:00:00.001-07:00

Oral anti-viral medications are associated with a reduced risk of recurring eye disease caused by herpes simplex virus, researchers found.
In a retrospective analysis of patient data covering a period of 32 years, those not taking prophylactic anti-viral drugs had a markedly increased risk of epithelial keratitis, stromal keratitis, blepharitis, or conjunctivitis, according to Keith Baratz, MD, and colleagues at the Mayo Clinics in Rochester, Minn., and Jacksonville, Fla.

Patients who experienced a serious adverse outcome of the herpes infection -- such as loss of vision -- were only rarely taking prophylactic drugs, Baratz and colleagues reported in the September issue of Archives of Ophthalmology.

Getting Tested for Herpes

2010-09-10T05:58:00.000-07:00

Does testing positive for herpes mean you will inevitably have outbreaks? Does a positive herpes test result always mean you can spread genital herpes to others? These are among the questions raised by readers of the Consults blog. Dr. Peter Leone, associate professor at the University of North Carolina School of Medicine and Public Health, addresses testing for the two types of herpes simplex virus: HSV-2, the main cause of genital herpes, and HSV-1, responsible for most cases of oral herpes, or cold sores.

Herpes Drugs May Be Safe in Early Pregnancy

2010-09-03T17:18:00.000-07:00

Taking certain antiviral medications for herpes infections during the first three months of pregnancy does not increase a child's risk of major birth defects, researchers report in this week's issue of the Journal of the American Medical Association.

The antiviral drugs acyclovir, valacyclovir, and famciclovir are often prescribed to treat herpes viral infections, such as herpes simplex virus (HSV). More than one in five pregnant women have antibodies in their blood to HSV, indicating a past or present infection.

Study: Herpes Drugs Don't Cause Birth Defects

2010-08-25T19:52:00.000-07:00

New Study Reveals Herpes Drugs Don't Cause Birth Defects

The most common types of the Herpes Simplex Virus (HSV) are: type 1 oral herpes (HSV-1), causing sores around the mouth and lips referred to as fever blisters or cold sores; type 2, genital herpes (HSV-2) causing sores around the genitals or rectum or other locations below the waist; Herpes Zoster Virus causing chickenpox and shingles.

Are Warts Related to Herpes?

2010-08-19T17:25:00.000-07:00

Can warts on the hand lead to anal or genital infections? Are warts a form of herpes? Those are among the questions readers recently posed to the Consults blog. Dr. Peter Leone, associate professor at the University of North Carolina School of Medicine and Public Health, responds.

Antigenics posts positive herpes drug study data

2010-08-11T18:42:00.000-07:00

Antigenics reported positive data Tuesday from an early stage clinical therapy trial to treat herpes simplex virus-2, the virus that causes genital herpes.

The trial was designed to evaluate a drug designated AG-707, which is designed to stimulate two types of T cells. Antigenics enrolled 35 patients in the trial. They received either AG-707, a combination of AG-707 and an adjuvant called QS-21, QS-21 alone, or a placebo.

Genetically Engineered Herpes Virus to Treat Cancer of Mouth

2010-08-05T17:17:00.001-07:00

A team of doctors have made use of genetically engineered herpes virus, in order to treat cancer of mouth, head and neck.

The Institute of Cancer Research and the Royal Marsden NHS Foundation Trust carried out a trial on 17 patients, who had been jabbed with the virus, as well as underwent chemotherapy and radiotherapy.

Onco VEX, which is the cold sore virus, was tailored in such a way to multiply inside cancer cells, however not in the cells that are healthy.

Promise for Herpes, Staph Sufferers Shown in Probiotic-Derived Immune Support Supplement

2010-07-29T04:43:00.001-07:00

Dr. Lubov Shynkarenko, vice president and lead researcher of Pure Research Products, LLC, recently presented findings that demonstrate the company's probiotic-derived supplement's potential to support the immune system while it staves off viruses and infections like herpes and staph.

Mice were infected with herpes simplex virus-1 and Staphylococcus aureus for the study, which was revealed by Dr. Shynkarenko at this spring's International Probiotics Association (IPA) World Congress. Del-Immune V demonstrated strong protective action, with a significant increase in survival rate among mice that were given the product. Pure Research Products hopes these promising results will pave the way for clinical trials that further substantiate the effectiveness of the supplement's immune support for sufferers of viruses and infections. Del-Immune V is derived from the probiotic lactobacillus rhamnosus (DV strain), which was authored in the Ukraine by Dr. Shynkarenko.

Got herpes? Get tumeric

2010-07-15T18:46:00.000-07:00

The plant's medicinal uses run the gamut of inflammations and sprains, herpes, jaundice and for strengthening the immune system.

For inflammations, you may beat the turmeric and apply the poultice to the affected areas where it can work in less than 15 minutes to reduce the swelling.

Research Sheds Light on How Herpes Virus Invades Cells

2010-07-10T19:37:00.001-07:00

U.S. scientists believe they are getting closer to understanding how the herpes simplex virus invades cells, potentially providing a target for new drugs to fight the virus, researchers say.

The scientists used advanced imaging technologies to learn more about the structure and function of the cell-entry protein complex used by the herpes simplex virus type 2 (HSV-2), which causes genital herpes.

Giving Your Partner Herpes

2010-06-26T05:27:00.000-07:00

Can someone infected with herpes continue to have sex without giving it to their partner? Do cold sores, which are almost always caused by herpes simplex virus type 1 (HSV-1), protect against genital herpes caused by herpes simplex virus type 2? Can someone be infected with both types of herpes viruses?

Those are among the questions recently posed by readers of the Consults blog. Dr. Peter Leone, an expert on sexually transmitted diseases and associate professor at the University of North Carolina School of Medicine and Public Health, responds...

Mylan says FDA approves generic herpes drug

2010-06-02T14:26:00.000-07:00

Generic drugmaker Mylan Inc. said Wednesday that it started shipping its version of GlaxoSmithKline's herpes drug Valtrex after winning approval from the Food and Drug Administration.

Mylan is shipping generic versions of Valtrex, or valacyclovir, in 500 milligram and 1000 milligram strengths. Sales of the drug totaled $2.15 billion in sales for the 12 months ended March 31, Mylan said.

Companies including Dr. Reddy's Laboratories, Sandoz, and Teva Pharmaceutical Industries are also making generic versions of the drug.

What to Ask About Herpes

2010-05-26T17:43:00.001-07:00

The most common signs are sores orulcers on the genitals, as well as general pain or itching around the groin. These symptoms can flare up for a few days and then disappear, with the first outbreak often being the most severe. As many as 80 percent who have herpes, however, do not notice anything wrong, or think their symptoms are an unrelated problem. A blood test can confirm if you have one of the two viruses that cause genital herpes.

Herpes Simplex - Drug Pipeline Analysis and Market Forecasts to 2016

2010-05-07T07:24:00.001-07:00

The global herpes simplex therapeutics market was worth approximately $2.9 billion in 2009. In 2001 the market was valued at approximately $1 billion and it grew at an approximate Compound Annual Growth Rate (CAGR) of 14% from 2001 to 2009. The global Herpes Simplex therapeutics market is expected to reach $6 billion by 2016, growing at a CAGR of 11.1%. The primary factor contributing to the increase in revenues over the forecast period is the increase in disease incidence. Presently, the therapeutic regimen for herpes simplex is dominated by a range of DNA polymerase inhibitors which include Zovirax, Famvir, Valtrex, Denavir and OTC (Over The Counter) products such as Abreva and Aviralex. This market is a significantly genericized market, with many brands across the seven geographies covered. Tablet prices range between $1 and $3 depending on the brand. The average annual cost of therapy for herpes simplex therapeutics ranges between $725 and $2,050 based on the treatment regimen (reduction or suppression therapy).

FDA grants final approval for generic form of anti-herpes drug Valtrex

2010-04-21T18:22:00.000-07:00

Individuals in the United States suffering from conditions such as genital herpes, cold sores, chickenpox, and herpes zoster(shingles) can now receive the generic form of the prescription antiviral drug Valtrex, (valacyclovir hydrochloride), thanks to the approval granted recently by the Food and Drug Administration(FDA) to drug manufacturer, Ranbaxy Laboratories. Ranbaxy is the first pharmaceutical manufacturer entitled to offer an affordable alternative to the brand.

Herpes more common than thought

2010-04-15T14:27:00.000-07:00

Genital herpes is known for the sores and blisters it causes. According to Larry Shockley, a health educator for the Oklahoma State Department of Health, there are two types of herpes. Herpes 1 is associated with the lips and herpes 2 is associated with the genitals. The sores caused by herpes 2 come in clusters that cause stinging or burning when urinating. The place where the sores appear is the original site where the virus entered the body. The first outbreak usually occurs within two weeks after the virus enters the body, and generally takes two to four weeks to heal. Other symptoms include a second set of sores and flu-like symptoms, including fevers and swollen glands. Â However, people infected with herpes often have no symptoms, or might mistake mild symptoms for insect bites or another skin condition. According to Shockley, every cold sore and fever blister is a type of herpes virus.

Health Buzz: 1 in 6 Americans Has Genital Herpes

2010-04-03T19:34:00.000-07:00

The sexually transmitted strain of herpes simplex virus infects 1 out of every 6 Americans, HealthDay reports. Luckily, the rate of infection is not increasing, according to a new report by the Centers for Disease Control and Prevention. But the agency did find that certain groups are more at risk. The infection rate in women, for example, was almost double the rate in men, while three times as many blacks as whites were infected, the report showed. Among those who reported having a history of 10 or more sex partners, 27 percent had herpes, compared with 4 percent of those with one lifetime sex partner, HealthDay reports.

Single, Black, Infected? Black Women and Genital Herpes

2010-03-26T13:13:00.000-07:00

Black women don't always have the best reputations. I mean, we're single, bitchy, and supposedly way too professional to ever please a man. Not to mention, the Centers for Disease Control decided to ruin our mojo with the recently released information that 48 percent of black women between the ages of 14 and 49 have the virus that causes genital herpes.

Health Buzz: 1 in 6 Americans Has Genital Herpes

2010-03-19T14:21:00.001-07:00

1 in 6 Americans Has Genital Herpes

CDC Says Genital Herpes in Americans is High

2010-03-12T15:39:00.000-08:00

According to a report released Tuesday from the CDC, approximately 16 percent of Americans are currently infected with genital herpes, a statistic that reveals theSexually Transmitted Disease as one of the most common sex-related ailments in the US.

Patient trials of genital herpes vaccine begin in London

2010-03-06T13:21:00.000-08:00

A new vaccine designed to prevent people with genital herpes from passing the virus on to their sexual partners has begun its first patient trials at a hospital in England.

Two healthy volunteers have been given the jab at the Chelsea and Westminster Hospital in London, in the first phase of a study that could eventually provide the first effective immunization against the incurable sexually transmitted infection.

The safety trial, which will eventually involve 42 people, comes after encouraging results in animal models, the Times Online reported March 4.

Herpes Drug Might Also Slow HIV Progression

2010-02-20T17:36:00.000-08:00

New research suggests that people who are infected with both HIV-1, a strain of the AIDS virus, and herpes simplex virus type 2 could benefit in more than one way by taking a herpes drug called acyclovir. In addition to treating herpes, the medication appears to also slow the progression of HIV.

Herpes Medication Does Not Reduce Risk of HIV Transmission, Study Finds

2010-02-13T05:44:00.001-08:00

A five-year international multi-center clinical trial has found that acyclovir, a drug widely used as a safe and effective treatment taken twice daily to suppress herpes simplex virus-2 (HSV-2), which is the most common cause of genital herpes, does not reduce the risk of HIV transmission when taken by people infected with both HIV and HSV-2.

Genital Herpes' Reactivation Better Understood

2010-01-30T12:37:00.000-08:00

Genital herpes frequently reactivates throughout the genital tract, a finding that may help improve treatment and prevention, U.S. researchers say.

Over 30 days, the investigators collected daily samples from seven separate genital sites in four women infected with herpes simplex virus type 2 (HSV-2). HSV-2 was detected on more than one area on 56 percent of days when there was viral shedding and on genital surfaces on both sides of the women's bodies on most days when HSV-2 was detected at more than one site, according to the researchers at the University of Washington and the Fred Hutchinson Cancer Research Center in Seattle.

Coffee Cuts Liver Scarring in Hepatitis C

2010-01-09T06:21:00.001-08:00

Caffeine in coffee reduces the severity of liver fibrosis in patients with chronic hepatitis C virus, a new study has found.

Liver fibrosis (scarring of the liver) is the second stage of liver disease during which liver function declines because of accumulated connective tissue.

Sleeping Beauty teams up with herpes to fight brain diseases

2010-01-09T06:18:00.001-08:00

Scientists from University of Rochester Medical Centre have developed a gene therapy by bringing together herpes virus and a molecule, which will help fight diseases of the brain and nervous system.

Genital Herpes May Never Go Dormant - US News and World Report

2009-11-20T15:03:00.000-08:00

"Herpes, the sexually transmitted disease that causes genital lesions, never truly goes into a dormant state, new research suggests.
Click here to find out more!

As a matter of fact, even when it's not causing an outbreak, the virus is shedding tiny bits of itself in the genital tract."

Vital Signs - Study Links Exposure to 5 Pathogens With Higher Risk for Stroke - NYTimes.com

2009-11-14T15:36:00.000-08:00

"A new study is linking cumulative exposure to five common pathogens with an increased risk for stroke. The infections in order of significance are Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus and herpes simplex viruses 1 and 2, according to the study, published online on Nov. 9 in The Archives of Neurology. “Each of these common pathogens may persist after an acute infection and contribute to perpetuating a state of chronic low-level infection,” said the paper’s lead author, Dr. Mitchell S. V. Elkind, an associate professor of neurology at Columbia University Medical Center."

Eyebrow Waxing Can Spread Herpes - Health News Story - KCRA Sacramento

2009-11-06T06:39:00.000-08:00

"Some women consider the 10 minutes spent on monthly eyebrow waxes critical to a polished, clean and professional look. But eyebrow waxing can spread a form of herpes and lead to blindness, WCVB in Boston reported."

Black PR Wire, Inc. - Press Releases

2009-10-23T08:25:00.000-07:00

"Genital herpes impacts millions of lives each year. According to the Centers for Disease Control and Prevention, at least 45 million people ages 12 and older, or one out of five adolescents and adults, have had genital herpes simplex virus infection. The disease may cause recurrent painful genital sores in adults, suppress an adult’s immune system, play a role in the spread of Human Immunodeficiency Virus (HIV), and can lead to potentially fatal infections in babies."

Conjunctivitis, herpes simplex 1, and hepititis oh my

2009-10-16T11:53:00.000-07:00

"Conjunctivitis, herpes simplex 1, and hepatitis C can all be spread through dirty makeup brushes and if you don't ask you'll never know if the brushes used on you have been sanitized since the last makeup counter patron to get their makeup done. Its simple, ask or risk infections."

HealthNewsDigest.com

2009-10-09T08:03:00.000-07:00

"It’s probably not something you discuss with your friends, but you almost certainly know several people who are infected with genital herpes. The Centers for Disease Control & Prevention (CDC) estimates that as many as 45 million people ages 12 and older have this very common sexually transmitted disease. That equates to about one in five adolescents and adults."

NEJM -- Maternal and Neonatal Herpes Simplex Virus Infections

2009-10-03T06:49:00.000-07:00

"An estimated 25 to 65% of pregnant women in the United States have genital infection with herpes simplex virus type 1 (HSV-1) or HSV type 2 (HSV-2).1 Neonatal HSV infection, defined as infection in a newborn within 28 days after birth, is an especially devastating consequence of the epidemic of genital herpes. Untreated neonatal HSV infection is associated with only a 40% survival rate, and even with the early initiation of high-dose intravenous acyclovir therapy, it results in considerable disability among survivors."

Jackson Estate Sued over 'Herpes Cure' | TMZ.com

2009-09-24T08:45:00.000-07:00

"A man is suing Michael Jackson's estate, claiming the singer is responsible for the theft of his herpes cure.

Erle Bonner claims Jackson gave his formulas for 'herpes cure, acne cures and arthritis cures' to a guy named Kevin Trudeau, also a defendant, who allegedly pilfered them."

SEE - Edmonton Sex - My Messy Bedroom - Shiny Herpes People

2009-09-11T11:19:00.000-07:00

"Genital herpes is more common than people like to think: there’s no reporting system in Canada for herpes, but a U.S. survey estimates that one in six people has the virus, with eight out of every 10 infected people unaware of their condition."

Herpes testing could shed light on risk for vision problems

2009-08-01T05:07:00.000-07:00

"Scientists have found that patients who had a positive result from a herpes test may be at an increased risk for damage to their cornea, the clear coating in one's eyes, and a new study suggests that the sexually transmitted virus could also limit future treatments."

Gonorrhoea down as herpes rises | Herald de Paris

2009-07-24T11:53:00.000-07:00

"Statistics from the Health Protection Agency (HPA) showed the number of new gonorrhoea infections was the lowest in nearly a decade.

Overall sexually transmitted infections was up last year by 0.5%, mostly due to the increase in herpes and warts.

Those aged between 16 to 24 are still disproportionately affected by STIs.

While just 12% of the UK population falls into this age group, they account for more than half of all new STIs diagnosed in the UK."

To reduce the risk of genital herpes, use a condom -- every time | Booster Shots | Los Angeles Times

2009-07-17T13:54:00.000-07:00

"We've assumed that condoms can reduce the spread of genital herpes -- but without complete, or at least well-quantified, confidence in the assumption.

This fact sheet from the federal Centers for Disease Control and Prevention sums up the reason for such hesitation: 'Genital ulcer diseases can occur in both male and female genital areas that are covered or protected by a latex condom, as well as in areas that are not covered.'"

'Stealth' Herpes Simplex Inflammation Impacts Corneal Transplants

2009-07-10T13:28:00.000-07:00

"The herpes simplex virus (HSV) can infect the eye and sometimes causes so much damage that the person's cornea must be replaced with a transplant. (The cornea is the clear covering of the front of the eye that helps focus light for vision.) Doctors knew transplants were more likely to fail in people with HSV than in patients with other disorders, such as keratoconus, an abnormal steepening of the cornea."

MCV - Melbourne Community Voice for Gay and Lesbian Readers - Herpes Survey Down Under - MCV - Melbourne Community Voice for Gay and Lesbian Readers

2009-07-03T06:46:00.000-07:00

"The nationwide Genital Herpes Patient Perspectives Survey aims to provide an up-to-date snapshot of Australians living with genital herpes, to improve clinical understanding of patient experiences, and help identify the most effective treatments available for genital herpes."

Herpes Simplex Q & A

2009-06-26T18:51:00.000-07:00

"In this piece I’d like to do a question and answer article using some very common questions.

What is the difference between herpes simplex virus (HSV) type 1 and type 2?

They are 2 different serotypes that infect humans. HSV type 1 most commonly infects the mouth and lips, causing sores known as fever blisters (95%). It is also an important cause of genital infection."

Herpes facts - CBS 12 Action News

2009-06-18T18:13:00.000-07:00

"Herpes is a disease caused by the herpes simplex virus, or HSV (H-S-V). The virus is usually transmitted by direct contact with an infected individual, including kissing, oral sex, and sexual intercourse, or other situations in which viruses from the infection site contact broken skin or a mucous membrane like the mouth. HSV-type 1 most often results in 'fever blisters' or 'cold sores' around the mouth. HSV-type 2 typically causes lesions in the genital area. However, either virus can be spread to the opposite location."

Mmegi Online :: Herpes medication does not reduce HIV transmission

2009-06-12T07:38:00.000-07:00

"Herpes medication does not reduce the risk of HIV transmission from individuals with HIV and genital herpes, Dr Joseph Makhema revealed at a press briefing held last Thursday at the Botswana Harvard Partnership buildings in Gaborone"

Medical News: ICD: Herpes Virus Linked to Psoriasis - in Meeting Coverage, ICD from MedPage Today

2009-06-05T07:39:00.000-07:00

"More than half of a group of patients with psoriasis tested positive for human herpes virus 8 (HHV-8), suggesting infection might play a role in the etiology of the disease, according to data reported here."

Medical Updates - Herpes Virus May Be Treatment for Late Stage Melanoma | Health News

2009-05-29T14:42:00.000-07:00

"Intensive research has recently been completed on melanoma, the most deadly form of skin cancer, and now we have new evidence that a form of the herpes virus, best known for causing cold sores, has shown effectiveness when treating late stage melanoma. While researchers aren’t positive as to the cause of melanoma, exposure to ultraviolet radiation from the sun or tanning booths increase risks."

TwoCan.com :: Premier Herpes Dating Website, www.TwoCan.com, to Aid in Finding a Cure for Herpes

2009-05-22T07:47:00.000-07:00

"TwoCan.com(TM) announces today the full release of its herpes dating website, www.TwoCan.com and its commitment to help find a cure by donating a percentage of profits to Duke University's herpes research. TwoCan.com is the first and only dating site created exclusively to help millions of people with HSV-2 (herpes) by eliminating the fear of disclosure and exposure."

DAILY NATION - New study urges male cut to fight herpes and Aids

2009-05-15T13:59:00.000-07:00

"Male circumcision reduces chances of contracting the herpes virus that accelerates Aids-related deaths, according to experts.

Medical researchers from the University of Nairobi, Moi Referral Hospital, University of Washington and the Kenya Government said the virus, known as HSV-2, subjects Aids patients to a double blow in their immunity.

In view of this, they added, male circumcision is vital in protecting couples from the two deadly killer viruses. The team of experts, led by the National Aids/STI Programme director, Dr Nicholas Muraguri, said many people with HIV/Aids also have herpes."

European Biotechnology News :: Molecular link between herpes and cancer

2009-05-07T12:18:00.000-07:00

"Lisbon/New York - A Portuguese-US research team has discovered a new molecular mechanism that enables gamma herpes viruses to chronically infect patients. Gamma herpes viruses infect white blood cells (B- or T-lymphocytes) remaining latent in the lymphoid tissues as an asymptomatic chronic infection. The results of the study, which were published online in the EMBO Journal, offer a greater understanding of why these patients are more likely to suffer from lymphocyte (white blood cell) cancer lymphoma immunodeficiency."

Man claims $200,000 for herpes - Canada - Macleans.ca

2009-05-01T08:48:00.000-07:00

"Is getting a rare disease an “accident”? Randolph Gibbens, who was paralyzed after contracting herpes, believes so. But his insurer, which is fighting his workplace disability claim, contends that if diseases are considered accidents, then everyone’s insurance premiums could skyrocket.

After Gibbens, 48, had unprotected sex with three women in early 2003, he developed herpes simplex type 2. The disease progressed into a rare inflammation in his spinal cord, and within weeks he was paralyzed from the mid-abdomen down. Gibbens, who lives in Port Coquitlam, B.C., and worked as a high pressure water blaster, was insured by Co-operators Life Insurance. His accidental disease or dismemberment plan pays $200,000 for “proof of paraplegia” or lost use of his legs due to “external, violent and accidental means.”"

Herpes for richer for poorer

2009-04-29T12:35:00.000-07:00

"Genital herpes is an infection that rich Australian men share with poor and uneducated women, a national study of the socioeconomic distribution of HSV-2 suggests.

Using serum samples from more than 4000 people picked at random for the AusDiab study, researchers at the School of Public Health at the University of Queensland looked at how seropositivity for herpes simplex type 2 correlated with socioeconomic status, place of residence and levels of education.

Their findings, published in Sexually Transmitted Diseases (online March 26) show that rates of HSV-2 were generally higher in wealthy areas compared to poor areas of Australia."

The All New Online Private Dating Community Exclusively for Herpes is here!

2009-04-25T11:35:00.000-07:00

"Online dating has developed a lot in the last few years and it’s gaining more significance. It is very popular in all kinds of places and people, and even it had involved herpes people.

(live-PR.com) - April 24, 2009 - Dating is one of the best ways to connect people all around the world. Through this, many people get to know each other and more over many ends up in relationships. Online dating has caught the eye of several which is very easy and fast too."

Herpes drug may help control AIDS virus

2009-04-22T14:08:00.000-07:00

"A cheap, generic drug long used to treat herpes may also help control the AIDS virus, U.S. researchers reported on Wednesday.

They found that acyclovir can work against HIV, but only in tissues that are also infected with herpes.

The findings, published in the journal Cell Host & Microbe, help explain why some studies have shown that people taking acyclovir have lower levels of HIV, yet others show that taking acyclovir does not prevent infection with the AIDS virus."

Cellular process fights type 1 herpes - UPI.com

2009-04-15T10:48:00.000-07:00

Canadian and U.S. researchers have identified a cellular process that seeks out and fights type 1 herpes simplex -- cold sores.

The five-year study, a joint project with the University of Montreal, Washington University and Pennsylvania State University, found that the nuclear membrane of an infected cell can unmask type 1 herpes simplex and stimulate the immune system to disintegrate the virus."

No More Cold Sores? Scientists Find Cellular Process That Fights Herpes Virus

2009-04-13T11:03:00.000-07:00

"Scientists have discovered a new way for our immune system to combat the elusive virus responsible for cold sores: Type 1 herpes simplex (HSV-1). As reported in the advance online edition of Nature Immunology, a group of virus hunters from the Université de Montréal, in collaboration with American colleagues, have identified a cellular process that seeks out and fights herpes."

Herpes simplex virus infection in pregnancy and in neonate:status of art of epidemiology, diagnosis, therapy and prevention - 7thSpace Interactive

2009-04-08T13:05:00.000-07:00

"Herpes simplex virus (HSV) infection is one of the most common viral sexually transmitted diseases worldwide. The first time infection of the mother may lead to severe illness in pregnancy and may be associated with virus transmission from mother to foetus/newborn.Since the incidence of this sexually transmitted infection continues to rise and because the greatest incidence of herpes simplex virus infections occur in women of reproductive age, the risk of maternal transmission of the virus to the foetus or neonate has become a major health concern.On these purposes, this review shows the recent studies on the knowledge of the status of art of epidemiology, diagnosis, therapy and prevention of HSV in pregnant women and neonate.The Authors of this review looked for the medical literature and pertinent publications in particular to understand the importance of genital herpes simplex virus infection in pregnancy."

Protein Seen to Play Role in Herpes Reactivation - Expression of VP16 appears to start the lytic cycle of the herpes simplex virus - Modern Medicine

2009-04-01T13:39:00.000-07:00

Expression of a virion protein called VP16 appears to be necessary for herpes simplex virus to exit its latent state, according to research published in the March issue of PLoS Pathogens.

Richard L. Thompson, Ph.D., of the University of Cincinnati School of Medicine, Ohio, and colleagues used a mouse model of ocular herpes simplex virus pathogenesis along with viral mutants to assess latency and exit from latency at a neuronal level."

Male Circumcision Reduces Risk Of Genital Herpes And HPV Infection, But Not Syphilis

2009-04-01T13:38:00.000-07:00

"Male Circumcision Reduces Risk Of Genital Herpes And HPV Infection, But Not Syphilis

Heterosexual men who undergo medical circumcision can significantly reduce their risk of acquiring two common sexually transmitted infections--herpes simplex virus type 2 (HSV-2), the cause of genital herpes, and human papillomavirus (HPV), which can cause cancer and genital warts, according to a report in the March 26 issue of the New England Journal of Medicine (NEJM). In the study, circumcision had no effect on their risk of becoming infected with the bacterium that causes syphilis, however."

Oxycodone Effective for Herpes Zoster Pain Relief - Randomized trial finds drug superior to gabapentin and placebo in relieving pain - Modern Medicine

2009-04-01T13:37:00.000-07:00

"In patients with herpes zoster, controlled-release oxycodone effectively relieves pain and is generally well-tolerated, according to a study published in the April issue of Pain.

Robert H. Dworkin, Ph.D., of the University of Rochester School of Medicine and Dentistry in Rochester, N.Y., and colleagues randomly assigned 87 patients to receive seven days of treatment with famciclovir in combination with 28 days of treatment with either controlled-release oxycodone, gabapentin or placebo."

BBC NEWS | UK | England | Wiltshire | Monkey jungle closed by herpes

2009-03-27T09:42:00.000-07:00

"Monkey jungle closed by herpes

The drive-through monkey jungle at Longleat in Wiltshire has closed after a monkey was found to have herpes.

Only one creature in the group, a female, was found to have Simian Herpes during routine tests of the rhesus monkey colony at the safari park.

Longleat said the jungle will remain closed while they investigate how the monkey tested positive as none of the other monkeys have done so.

The monkeys are regularly tested by the Health Protection Agency."

Treatment Target for Herpes Pinpointed - US News and World Report

2009-03-27T09:41:00.000-07:00

"Treatment Target for Herpes Pinpointed
Study finds VP16 is molecular key that unlocks the virus from latent state

Researchers have identified a potential new target in the ongoing quest for a treatment, and possibly a cure, for the herpes virus.

A viral protein known as VP16 is apparently responsible for pushing herpes out of its latent state and back into an active infectious state."

Male circumcision reduces herpes, study finds

2009-03-27T09:37:00.000-07:00

"Male circumcision reduces herpes, study finds
But national circumcision rate is declining; local doctor wants to reassess advice to parents

A new study in this week's New England Journal of Medicine found that male circumcision decreased rates of two common sexually transmitted diseases -- a finding that may help reverse the declining circumcision rate in the country.

The study, conducted by researchers from Uganda and Johns Hopkins University, found that adult male circumcision significantly decreased rates of herpes and the human papillomavirus, which causes genital warts. The study follows three landmark trials from Africa that showed that the procedure reduced HIV rates by up to 60 percent."

Circumcision trial shows how HIV and herpes amplify each other: circumcision protects against both

2009-03-20T12:04:00.000-07:00

Circumcision trial shows how HIV and herpes amplify each other: circumcision protects against both:

New findings from the South African randomised controlled trial (RCT) of circumcision have found that HIV and herpes simplex virus 2 (HSV-2) independently reinforce each others’ effects. People with one infection in the study were more likely to acquire the other infection. The study also found that circumcision protected men in the study against HSV-2 as well as HIV."

FOXNews.com - Lawyer: Woman Unknowingly Infected With Herpes Awarded Nearly $7 Million - Health News | Current Health News | Medical News

2009-03-19T05:37:00.000-07:00

"Lawyer: Woman Unknowingly Infected With Herpes Awarded Nearly $7 Million"

Lifestyle: Protecting Partners from Herpes

2009-03-14T08:20:00.000-07:00

Lifestyle: Protecting Partners from Herpes: "Protecting Partners from Herpes

Condom 'I was diagnosed with genital herpes. I can't wear protection as I am skin sensitive to latex. What can I do to protect future partners? If we have oral sex how can I protect him from this virus? I am not on meds for it.'

The good news for those allergic to latex: you can wear protection. Because latex allergies are relatively common, there are latex-free-condoms made of polyurethane. Polyurethane condoms come in both male and female forms—the female condom fits inside the vagina and the male polyurethane condom is identical to its latex brother and feels equally great."

St. Paul Legal Ledger

2009-03-12T07:40:00.000-07:00

"Early syphilis cases were up 40 percent in Minnesota in 2008, compared with a year earlier, and health officials are expressing concern over the rise.

Early syphilis, or infection of less than a year, is the most infectious stage of the disease.

Preliminary data from the Minnesota Department of Health show that 159 early syphilis cases were reported in 2008, compared to 114 cases in 2007. Of the cases in 2008, 97 percent were males, and new infections continued to be centered within the Twin Cities metropolitan area."

Explore Howard: Sidelines - Skin infection costs two wrestlers

2009-03-12T07:38:00.000-07:00

"Every Maryland wrestler’s dream is to end their season with a trip to the state tournament at Cole Field House. For two county wrestlers that dream was dashed by mat herpes, a skin infection also known Herpes gladiatorum. Mat herpes is a variant of the herpes simplex virus that can be spread through the type of physical contact inherent to wrestling."

STDs: Immorality’s Plague

2009-03-06T14:11:00.000-08:00

"When the United States government published its statistics for sexually transmitted diseases in 2006, the numbers were shocking. Chlamydia had topped one million newly reported cases for the first time. Syphilis cases jumped 14 percent over the previous year. And a new drug-resistant strain of gonorrhea plagued the nation."

BBC NEWS | England | Lancashire | Grieving mother's herpes warning

2009-03-02T14:08:00.000-08:00

"The mother of a baby who died after contracting herpes from her cold sores is campaigning for more awareness of how dangerous it can be to newborns.

Jennifer Schofield was 11 days old when her organs failed after contracting the Herpes Simplex Virus (HSV), through either kisses or breastfeeding."

The Associated Press: Woman infected with herpes wins $7M in Calif. suit

2009-02-27T01:05:00.000-08:00

The Associated Press: Woman infected with herpes wins $7M in Calif. suit: "Woman infected with herpes wins $7M in Calif. suit

By LORINDA TOLEDO – 10 hours ago

LOS ANGELES (AP) — A jury awarded nearly $7 million to a 56-year-old woman who said she was unknowingly infected with herpes by the 77-year-old founder of a hair-care company.

The lawsuit alleged that Thomas Redmond knew he had genital herpes for more than 25 years but did not disclose it before his sexual relationship began with Patricia Behr, and did not use a condom."